Advances in Cardiology and Cardiovascular Disorders (ACCD)

Open Access Journal

Volume : 1 | Issue : 1

Proceeding

Genetics of fetal cardiac defects

Sujatha Jagadeesh

Department of Clinical Genetics, Mediscan Systems, Chennai, India

Received: November 10, 2017 | Published: November 14, 2017

Correspondence: Sujatha Jagadeesh, Department of Clinical Genetics, Mediscan Systems, Chennai 600004, India, Email genetics@mediscan.org.in

Copyright© 2017 Jagadeesh. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Proceeding

Fetal cardiac defects are being increasingly picked up with advances in fetal imaging technology and expertise. Most severe abnormalities are being picked up in first trimester. So knowledge on basis of these abnormalities becomes important in testing and counseling families. The development of the heart is very intricate and improper switch on and off of these genes lead to errors which are generally sporadic in nature. Errors in early cell division can cause chromosomal imbalances. Familial problems could occur due to errors in chromosomes, genes, mitochondria or can be multifactorial. Not all errors are genetic and one should consider teratogens like maternal diabetes, drugs as causative in some situations. Different case scenarios and how to work up for identifying the genetic basis will be amply illustrated in the lecture.